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Enhancement of UVB radiation-mediated apoptosis by knockdown of cytosolic NADP(+)-dependent isocitrate dehydrogenase in HaCaT cells
Ultraviolet B (UVB) radiation induces the production of reactive oxygen species (ROS) that promote apoptotic cell death. We showed that cytosolic NADP(+)-dependent isocitrate dehydrogenase (IDPc) plays an essential role in the control of cellular redox balance and defense against oxidative damage, b...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163888/ https://www.ncbi.nlm.nih.gov/pubmed/24286310 http://dx.doi.org/10.5483/BMBRep.2014.47.4.137 |