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Enhancement of UVB radiation-mediated apoptosis by knockdown of cytosolic NADP(+)-dependent isocitrate dehydrogenase in HaCaT cells

Ultraviolet B (UVB) radiation induces the production of reactive oxygen species (ROS) that promote apoptotic cell death. We showed that cytosolic NADP(+)-dependent isocitrate dehydrogenase (IDPc) plays an essential role in the control of cellular redox balance and defense against oxidative damage, b...

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Detalles Bibliográficos
Autores principales: Lee, Su Jeong, Park, Jeen-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163888/
https://www.ncbi.nlm.nih.gov/pubmed/24286310
http://dx.doi.org/10.5483/BMBRep.2014.47.4.137