Cargando…

Individual and collective responsibility to enhance regulatory compliance of the Three Rs

Investigators planning to use animals in their research and the Institutional Animal Care and Use Committee (IACUC) members who review the research protocols must take personal responsibility for ensuring that they have the skills and knowledge to perform their duties, applying the Three Rs principl...

Descripción completa

Detalles Bibliográficos
Autores principales: Choe, Byung In, Lee, Gwi Hyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163893/
https://www.ncbi.nlm.nih.gov/pubmed/24568878
http://dx.doi.org/10.5483/BMBRep.2014.47.4.049
_version_ 1782334884633640960
author Choe, Byung In
Lee, Gwi Hyang
author_facet Choe, Byung In
Lee, Gwi Hyang
author_sort Choe, Byung In
collection PubMed
description Investigators planning to use animals in their research and the Institutional Animal Care and Use Committee (IACUC) members who review the research protocols must take personal responsibility for ensuring that they have the skills and knowledge to perform their duties, applying the Three Rs principles of Russell and Burch. The two Korean laws introduced in 2008 and 2009 regulating animal use for scientific purposes in line with the Three Rs principles have been revised a total of 11 times over the last 6 years. Both regulatory agencies, e.g., the Animal and Plant Quarantine Agency and the Ministry of Food and Drug Safety, provide regular training based on the legal requirements. Based on the amended Animal Welfare Act, the IACUC appointment framework has been upgraded: appointments are now for two-year terms and require a qualified training certificate issued by the Animal and Plant Quarantine Agency since 2012. The authors reviewed the current curricular programs and types of training conducted by the two governing agencies through Internet searches. Our Internet survey results suggest that: a) diversity should be provided in training curricula, based on the roles, backgrounds and needs of the individual trainees; b) proper and continued educational programs should be provided, based on trainees’ experiences; and c) active encouragement by government authorities can improve the quality of training curricula. [BMB Reports 2014; 47(4): 179-183]
format Online
Article
Text
id pubmed-4163893
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Korean Society for Biochemistry and Molecular Biology
record_format MEDLINE/PubMed
spelling pubmed-41638932014-09-16 Individual and collective responsibility to enhance regulatory compliance of the Three Rs Choe, Byung In Lee, Gwi Hyang BMB Rep Review Article Investigators planning to use animals in their research and the Institutional Animal Care and Use Committee (IACUC) members who review the research protocols must take personal responsibility for ensuring that they have the skills and knowledge to perform their duties, applying the Three Rs principles of Russell and Burch. The two Korean laws introduced in 2008 and 2009 regulating animal use for scientific purposes in line with the Three Rs principles have been revised a total of 11 times over the last 6 years. Both regulatory agencies, e.g., the Animal and Plant Quarantine Agency and the Ministry of Food and Drug Safety, provide regular training based on the legal requirements. Based on the amended Animal Welfare Act, the IACUC appointment framework has been upgraded: appointments are now for two-year terms and require a qualified training certificate issued by the Animal and Plant Quarantine Agency since 2012. The authors reviewed the current curricular programs and types of training conducted by the two governing agencies through Internet searches. Our Internet survey results suggest that: a) diversity should be provided in training curricula, based on the roles, backgrounds and needs of the individual trainees; b) proper and continued educational programs should be provided, based on trainees’ experiences; and c) active encouragement by government authorities can improve the quality of training curricula. [BMB Reports 2014; 47(4): 179-183] Korean Society for Biochemistry and Molecular Biology 2014-04 /pmc/articles/PMC4163893/ /pubmed/24568878 http://dx.doi.org/10.5483/BMBRep.2014.47.4.049 Text en Copyright © 2014, Korean Society for Biochemistry and Molecular Biology http://creativecommons.org/licenses/by-nc/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Choe, Byung In
Lee, Gwi Hyang
Individual and collective responsibility to enhance regulatory compliance of the Three Rs
title Individual and collective responsibility to enhance regulatory compliance of the Three Rs
title_full Individual and collective responsibility to enhance regulatory compliance of the Three Rs
title_fullStr Individual and collective responsibility to enhance regulatory compliance of the Three Rs
title_full_unstemmed Individual and collective responsibility to enhance regulatory compliance of the Three Rs
title_short Individual and collective responsibility to enhance regulatory compliance of the Three Rs
title_sort individual and collective responsibility to enhance regulatory compliance of the three rs
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163893/
https://www.ncbi.nlm.nih.gov/pubmed/24568878
http://dx.doi.org/10.5483/BMBRep.2014.47.4.049
work_keys_str_mv AT choebyungin individualandcollectiveresponsibilitytoenhanceregulatorycomplianceofthethreers
AT leegwihyang individualandcollectiveresponsibilitytoenhanceregulatorycomplianceofthethreers