Demethylation of CpG islands in the 5' upstream regions mediates the expression of the human testis-specific gene MAGEB16 and its mouse homolog Mageb16

Tissue-specific gene expression is regulated by epigenetic modification involving trans-acting factors. Here, we identified that the human MAGEB16 gene and its mouse homolog, Mageb16, are only expressed in the testis. To investigate the mechanism governing their expression, the promoter methylation...

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Detalles Bibliográficos
Autores principales: Liu, Yunqiang, Wang, Meiling, Jiang, Siyuan, Lu, Yongjie, Tao, Dachang, Yang, Yuan, Ma, Yongxin, Zhang, Sizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163901/
https://www.ncbi.nlm.nih.gov/pubmed/24219866
http://dx.doi.org/10.5483/BMBRep.2014.47.2.066

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