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Component-Based Syntheses of Trioxacarcin A, DC-45-A1, and Structural Analogs

The trioxacarcins are polyoxygenated, structurally complex natural products that potently inhibit the growth of cultured human cancer cells. Here we describe syntheses of trioxacarcin A, DC-45-A1, and structural analogs by latestage, stereoselective glycosylation reactions of fully functionalized, d...

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Detalles Bibliográficos
Autores principales: Magauer, Thomas, Smaltz, Daniel J., Myers, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164168/
https://www.ncbi.nlm.nih.gov/pubmed/24056347
http://dx.doi.org/10.1038/nchem.1746

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