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OCH Ameliorates Bone Marrow Failure in Mice via Downregulation of T-Bet Expression

The aim of this study is to evaluate the immune mechanism of OCH in the treatment of AA (also named bone marrow failure, BMF) induced in mice. OCH at a dose of 400 μg/kg was injected intraperitoneally (I.P.) prior to the induction of BMF. Our study showed that the incidence of BMF was 100% in BMF gr...

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Detalles Bibliográficos
Autores principales: Qiao, Xiaohong, Xie, Xiaotian, Shi, Wei, Tang, Jinqing, Shao, Yuexia, Li, Fuxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164259/
https://www.ncbi.nlm.nih.gov/pubmed/25254224
http://dx.doi.org/10.1155/2014/928743