Cargando…

Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient

Primary Burkitt lymphoma of the central nervous system (CNS) is rare, with only few cases reported in the literature. An 18 year-old immunocompetent male presented with multiple cranial nerves palsies and was found to have a mass predominantly in the 4th ventricle of the brain. Tumor was surgically...

Descripción completa

Detalles Bibliográficos
Autores principales: Alabdulsalam, Abdulrahman, Zaidi, Syed Z. A., Tailor, Imran, Orz, Yasser, Al-Dandan, Sadeq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164299/
https://www.ncbi.nlm.nih.gov/pubmed/25254131
http://dx.doi.org/10.1155/2014/630954
_version_ 1782334937634963456
author Alabdulsalam, Abdulrahman
Zaidi, Syed Z. A.
Tailor, Imran
Orz, Yasser
Al-Dandan, Sadeq
author_facet Alabdulsalam, Abdulrahman
Zaidi, Syed Z. A.
Tailor, Imran
Orz, Yasser
Al-Dandan, Sadeq
author_sort Alabdulsalam, Abdulrahman
collection PubMed
description Primary Burkitt lymphoma of the central nervous system (CNS) is rare, with only few cases reported in the literature. An 18 year-old immunocompetent male presented with multiple cranial nerves palsies and was found to have a mass predominantly in the 4th ventricle of the brain. Tumor was surgically removed and showed morphological and immunohistochemical features consistent with Burkitt lymphoma. The patient responded very well to anthracycline based chemotherapy with high dose methotrexate (HD MTX) and intrathecal (IT) chemotherapy delivered by Ommaya reservoir. Primary Burkitt lymphoma of the CNS is a rare entity that poses differential diagnostic challenge with other small round blue cell tumors.
format Online
Article
Text
id pubmed-4164299
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-41642992014-09-24 Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient Alabdulsalam, Abdulrahman Zaidi, Syed Z. A. Tailor, Imran Orz, Yasser Al-Dandan, Sadeq Case Rep Pathol Case Report Primary Burkitt lymphoma of the central nervous system (CNS) is rare, with only few cases reported in the literature. An 18 year-old immunocompetent male presented with multiple cranial nerves palsies and was found to have a mass predominantly in the 4th ventricle of the brain. Tumor was surgically removed and showed morphological and immunohistochemical features consistent with Burkitt lymphoma. The patient responded very well to anthracycline based chemotherapy with high dose methotrexate (HD MTX) and intrathecal (IT) chemotherapy delivered by Ommaya reservoir. Primary Burkitt lymphoma of the CNS is a rare entity that poses differential diagnostic challenge with other small round blue cell tumors. Hindawi Publishing Corporation 2014 2014-08-31 /pmc/articles/PMC4164299/ /pubmed/25254131 http://dx.doi.org/10.1155/2014/630954 Text en Copyright © 2014 Abdulrahman Alabdulsalam et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Alabdulsalam, Abdulrahman
Zaidi, Syed Z. A.
Tailor, Imran
Orz, Yasser
Al-Dandan, Sadeq
Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient
title Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient
title_full Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient
title_fullStr Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient
title_full_unstemmed Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient
title_short Primary Burkitt Lymphoma of the Fourth Ventricle in an Immunocompetent Young Patient
title_sort primary burkitt lymphoma of the fourth ventricle in an immunocompetent young patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164299/
https://www.ncbi.nlm.nih.gov/pubmed/25254131
http://dx.doi.org/10.1155/2014/630954
work_keys_str_mv AT alabdulsalamabdulrahman primaryburkittlymphomaofthefourthventricleinanimmunocompetentyoungpatient
AT zaidisyedza primaryburkittlymphomaofthefourthventricleinanimmunocompetentyoungpatient
AT tailorimran primaryburkittlymphomaofthefourthventricleinanimmunocompetentyoungpatient
AT orzyasser primaryburkittlymphomaofthefourthventricleinanimmunocompetentyoungpatient
AT aldandansadeq primaryburkittlymphomaofthefourthventricleinanimmunocompetentyoungpatient