Cargando…
The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes
Leflunomide is an immunomodulatory agent used for the treatment of rheumatoid arthritis. In this study, we investigated the effect of A77 1726 – the active metabolite of leflunomide – on the production of IL-1 receptor antagonist (IL-1Ra) by human synovial fibroblasts and articular chondrocytes. Cel...
Autores principales: | Palmer, Gaby, Burger, Danielle, Mezin, Françoise, Magne, David, Gabay, Cem, Dayer, Jean-Michel, Guerne, Pierre-André |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416438/ https://www.ncbi.nlm.nih.gov/pubmed/15142263 http://dx.doi.org/10.1186/ar1157 |
Ejemplares similares
-
The active metabolite of leflunomide, A77-1726, increases proliferation of human synovial fibroblasts in presence of IL-1β
por: Magne, D, et al.
Publicado: (2004) -
Effects of leflunomide on interleukin-1 receptor antagonist (IL-1Ra) synthesis in chondrocytes and synovial fibroblasts
por: Palmer, G, et al.
Publicado: (2003) -
Production of interleukin-1 receptor antagonist by human articular chondrocytes
por: Palmer, Gaby, et al.
Publicado: (2002) -
The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes
por: Magne, David, et al.
Publicado: (2006) -
Production of interleukin (IL)-1 receptor antagonist by human articular chondrocytes
por: Palmer, G, et al.
Publicado: (2002)