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Treatment with recombinant interferon-β reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis

We investigated the therapeutic potential and mechanism of action of IFN-β protein for the treatment of rheumatoid arthritis (RA). Collagen-induced arthritis was induced in DBA/1 mice. At the first clinical sign of disease, mice were given daily injections of recombinant mouse IFN-β or saline for 7...

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Detalles Bibliográficos
Autores principales:	van Holten, Judith, Reedquist, Kris, Sattonet-Roche, Pascale, Smeets, Tom JM, Plater-Zyberk, Christine, Vervoordeldonk, Margriet J, Tak, Paul P
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416442/ https://www.ncbi.nlm.nih.gov/pubmed/15142270 http://dx.doi.org/10.1186/ar1165

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