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New Developed Cylindrical TM(010) Mode EPR Cavity for X-Band In Vivo Tooth Dosimetry

EPR tooth in vivo dosimetry is an attractive approach for initial triage after unexpected nuclear events. An X-band cylindrical TM010 mode resonant cavity was developed for in vivo tooth dosimetry and used in EPR applications for the first time. The cavity had a trapezoidal measuring aperture at the...

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Autores principales: Junwang, Guo, Qingquan, Yuan, Jianbo, Cong, Lei, Ma, Guofu, Dong, Guoshan, Yang, Ke, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164439/
https://www.ncbi.nlm.nih.gov/pubmed/25222483
http://dx.doi.org/10.1371/journal.pone.0106587
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author Junwang, Guo
Qingquan, Yuan
Jianbo, Cong
Lei, Ma
Guofu, Dong
Guoshan, Yang
Ke, Wu
author_facet Junwang, Guo
Qingquan, Yuan
Jianbo, Cong
Lei, Ma
Guofu, Dong
Guoshan, Yang
Ke, Wu
author_sort Junwang, Guo
collection PubMed
description EPR tooth in vivo dosimetry is an attractive approach for initial triage after unexpected nuclear events. An X-band cylindrical TM010 mode resonant cavity was developed for in vivo tooth dosimetry and used in EPR applications for the first time. The cavity had a trapezoidal measuring aperture at the exact position of the cavity’s cylindrical wall where strong microwave magnetic field H1 concentrated and weak microwave electric field E1 distributed. Theoretical calculations and simulations were used to design and optimize the cavity parameters. The cavity features were evaluated by measuring DPPH sample, intact incisor samples embed in a gum model and the rhesus monkey teeth. The results showed that the cavity worked at designed frequency and had the ability to make EPR spectroscopy in relative high sensitivity. Sufficient modulation amplitude and microwave power could be applied into the aperture. Radiation induced EPR signal could be observed remarkably from 1 Gy irradiated intact incisor within only 30 seconds, which was among the best in scan time and detection limit. The in vivo spectroscopy was also realized by acquiring the radiation induced EPR signal from teeth of rhesus monkey whose teeth was irradiated by dose of 2 Gy. The results suggested that the cavity was sensitive to meet the demand to assess doses of significant level in short time. This cavity provided a very potential option for the development of X-band in vivo dosimetry.
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spelling pubmed-41644392014-09-19 New Developed Cylindrical TM(010) Mode EPR Cavity for X-Band In Vivo Tooth Dosimetry Junwang, Guo Qingquan, Yuan Jianbo, Cong Lei, Ma Guofu, Dong Guoshan, Yang Ke, Wu PLoS One Research Article EPR tooth in vivo dosimetry is an attractive approach for initial triage after unexpected nuclear events. An X-band cylindrical TM010 mode resonant cavity was developed for in vivo tooth dosimetry and used in EPR applications for the first time. The cavity had a trapezoidal measuring aperture at the exact position of the cavity’s cylindrical wall where strong microwave magnetic field H1 concentrated and weak microwave electric field E1 distributed. Theoretical calculations and simulations were used to design and optimize the cavity parameters. The cavity features were evaluated by measuring DPPH sample, intact incisor samples embed in a gum model and the rhesus monkey teeth. The results showed that the cavity worked at designed frequency and had the ability to make EPR spectroscopy in relative high sensitivity. Sufficient modulation amplitude and microwave power could be applied into the aperture. Radiation induced EPR signal could be observed remarkably from 1 Gy irradiated intact incisor within only 30 seconds, which was among the best in scan time and detection limit. The in vivo spectroscopy was also realized by acquiring the radiation induced EPR signal from teeth of rhesus monkey whose teeth was irradiated by dose of 2 Gy. The results suggested that the cavity was sensitive to meet the demand to assess doses of significant level in short time. This cavity provided a very potential option for the development of X-band in vivo dosimetry. Public Library of Science 2014-09-15 /pmc/articles/PMC4164439/ /pubmed/25222483 http://dx.doi.org/10.1371/journal.pone.0106587 Text en © 2014 Junwang et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Junwang, Guo
Qingquan, Yuan
Jianbo, Cong
Lei, Ma
Guofu, Dong
Guoshan, Yang
Ke, Wu
New Developed Cylindrical TM(010) Mode EPR Cavity for X-Band In Vivo Tooth Dosimetry
title New Developed Cylindrical TM(010) Mode EPR Cavity for X-Band In Vivo Tooth Dosimetry
title_full New Developed Cylindrical TM(010) Mode EPR Cavity for X-Band In Vivo Tooth Dosimetry
title_fullStr New Developed Cylindrical TM(010) Mode EPR Cavity for X-Band In Vivo Tooth Dosimetry
title_full_unstemmed New Developed Cylindrical TM(010) Mode EPR Cavity for X-Band In Vivo Tooth Dosimetry
title_short New Developed Cylindrical TM(010) Mode EPR Cavity for X-Band In Vivo Tooth Dosimetry
title_sort new developed cylindrical tm(010) mode epr cavity for x-band in vivo tooth dosimetry
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164439/
https://www.ncbi.nlm.nih.gov/pubmed/25222483
http://dx.doi.org/10.1371/journal.pone.0106587
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