Mitotic phosphorylation of SUN1 loosens its connection with the nuclear lamina while the LINC complex remains intact

At the onset mitosis in higher eukaryotes, the nuclear envelope (NE) undergoes dramatic deconstruction to allow separation of duplicated chromosomes. Studies have shown that during this process of nuclear envelope breakdown (NEBD), the extensive protein networks of the nuclear lamina are disassemble...

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Detalles Bibliográficos
Autores principales: Patel, Jennifer T, Bottrill, Andrew, Prosser, Suzanna L, Jayaraman, Sangeetha, Straatman, Kees, Fry, Andrew M, Shackleton, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164488/
https://www.ncbi.nlm.nih.gov/pubmed/25482198
http://dx.doi.org/10.4161/nucl.36232

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