A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors

Genome hypomethylation is a common epigenetic alteration in human tumors, where it often leads to aberrant activation of a group of germline-specific genes, commonly referred to as “cancer-germline” genes. The cellular functions and tumor promoting potential of these genes remain, however, largely u...

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Detalles Bibliográficos
Autores principales: Loriot, Axelle, Van Tongelen, Aurélie, Blanco, Jordi, Klaessens, Simon, Cannuyer, Julie, van Baren, Nicolas, Decottignies, Anabelle, De Smet, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164501/
https://www.ncbi.nlm.nih.gov/pubmed/25089631
http://dx.doi.org/10.4161/epi.29628

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