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Structural Basis for Substrate Specificity of Mammalian Neuraminidases

The removal of sialic acid (Sia) residues from glycoconjugates in vertebrates is mediated by a family of neuraminidases (sialidases) consisting of Neu1, Neu2, Neu3 and Neu4 enzymes. The enzymes play distinct physiological roles, but their ability to discriminate between the types of linkages connect...

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Detalles Bibliográficos
Autores principales:	Smutova, Victoria, Albohy, Amgad, Pan, Xuefang, Korchagina, Elena, Miyagi, Taeko, Bovin, Nicolai, Cairo, Christopher W., Pshezhetsky, Alexey V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164519/ https://www.ncbi.nlm.nih.gov/pubmed/25222608 http://dx.doi.org/10.1371/journal.pone.0106320

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