Cargando…

CD166/ALCAM Expression Is Characteristic of Tumorigenicity and Invasive and Migratory Activities of Pancreatic Cancer Cells

BACKGROUND: CD166, also known as activated leukocyte cell adhesion molecule (ALCAM), is expressed by various cells in several tissues including cancer. However, the role of CD166 in malignant tumors is controversial, especially in pancreatic cancer. This study aimed to clarify the role and significa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fujiwara, Kenji, Ohuchida, Kenoki, Sada, Masafumi, Horioka, Kohei, Ulrich, Charles D., Shindo, Koji, Ohtsuka, Takao, Takahata, Shunichi, Mizumoto, Kazuhiro, Oda, Yoshinao, Tanaka, Masao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164537/ https://www.ncbi.nlm.nih.gov/pubmed/25221999 http://dx.doi.org/10.1371/journal.pone.0107247

Ejemplares similares

CD271(+) Subpopulation of Pancreatic Stellate Cells Correlates with Prognosis of Pancreatic Cancer and Is Regulated by Interaction with Cancer Cells
por: Fujiwara, Kenji, et al.
Publicado: (2012)

Pancreatic Cancer Cells Enhance the Ability of Collagen Internalization during Epithelial–Mesenchymal Transition
por: Ikenaga, Naoki, et al.
Publicado: (2012)

Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas
por: Shindo, Koji, et al.
Publicado: (2013)

Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells
por: Okumura, Takashi, et al.
Publicado: (2017)

Successful video-assisted thoracoscopic surgery in prone position in patients with esophageal cancer and aberrant right subclavian artery: report of three cases
por: Shindo, Koji, et al.
Publicado: (2017)

Numerous lymph node metastases in early gastric cancer without preoperatively enlarged lymph nodes: a case report
por: Tsutsumi, Chikanori, et al.
Publicado: (2020)

ALCAM (CD166) Expression and Serum Levels in Pancreatic Cancer
por: Tachezy, Michael, et al.
Publicado: (2012)

Clinical impact of remnant lymphatic invasion on the recurrence of esophageal squamous cell carcinoma after esophagectomy with neoadjuvant chemotherapy
por: Okuda, Sho, et al.
Publicado: (2022)

Necroptosis in pancreatic cancer promotes cancer cell migration and invasion by release of CXCL5
por: Ando, Yohei, et al.
Publicado: (2020)

Repeated Pancreatectomy for Recurrent Pancreatic Carcinoma after Pylorus-Preserving Pancreatoduodenectomy: Report of Two Patients
por: Ogino, Toshitatsu, et al.
Publicado: (2010)

Small-Sized, Flat-Type Invasive Branch Duct Intraductal Papillary Mucinous Neoplasm: A Case Report
por: Shindo, Koji, et al.
Publicado: (2013)

A rare case of PSA-negative metastasized prostate cancer to the stomach with serum CEA and CA19-9 elevation: a case report
por: Shindo, Koji, et al.
Publicado: (2020)

MicroRNA Expression as a Predictive Marker for Gemcitabine Response after Surgical Resection of Pancreatic Cancer
por: Ohuchida, Kenoki, et al.
Publicado: (2011)

Enhanced down-regulation of ALCAM/CD166 in African-American Breast Cancer
por: Tan, Fang, et al.
Publicado: (2014)

Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients
por: Donizy, Piotr, et al.
Publicado: (2015)

ALCAM/CD166 Is Involved in the Binding and Uptake of Cancer-Derived Extracellular Vesicles
por: Cardeñes, Beatriz, et al.
Publicado: (2022)

Thoracoscopic surgery combined with endoscopic creation of a submucosal tunnel for a large complicated esophageal leiomyoma
por: Oyama, Koki, et al.
Publicado: (2020)

ANGI-03 Functional roles of CD166/activated leukocyte cell adhesion molecule (CD166/ALCAM) for glioblastoma invasion
por: Kijima, Noriyuki, et al.
Publicado: (2020)

Inhibition of p600 Expression Suppresses Both Invasiveness and Anoikis Resistance of Gastric Cancer
por: Sakai, Hiroshi, et al.
Publicado: (2011)

N-acetyl cysteine induces quiescent-like pancreatic stellate cells from an active state and attenuates cancer-stroma interactions
por: Feng, Haimin, et al.
Publicado: (2021)

Activated leukocyte cell adhesion molecule (ALCAM or CD166) modulates bone phenotype and hematopoiesis
por: Hooker, R.A., et al.
Publicado: (2015)

ALCAM (CD166) as a gene expression marker for human mesenchymal stromal cell characterisation
por: Brinkhof, Bas, et al.
Publicado: (2020)

Inhibition of ERK1/2 in cancer-associated pancreatic stellate cells suppresses cancer–stromal interaction and metastasis
por: Yan, Zilong, et al.
Publicado: (2019)

Calpain inhibitor calpeptin suppresses pancreatic cancer by disrupting cancer–stromal interactions in a mouse xenograft model
por: Yoshida, Masaki, et al.
Publicado: (2016)

LIM only 4 is overexpressed in late stage pancreas cancer
por: Yu, Jun, et al.
Publicado: (2008)

MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation
por: Yu, Jun, et al.
Publicado: (2010)

Subtypes in pancreatic ductal adenocarcinoma based on niche factor dependency show distinct drug treatment responses
por: Shinkawa, Tomohiko, et al.
Publicado: (2022)

The Clinical and Theranostic Values of Activated Leukocyte Cell Adhesion Molecule (ALCAM)/CD166 in Human Solid Cancers
por: Yang, Yiming, et al.
Publicado: (2021)

Strong impact of sarcopenic state defined by skeletal muscle mass index on postoperative complication of Crohn's disease patients()
por: Nagayoshi, Kinuko, et al.
Publicado: (2023)

Prospectively Isolated Cancer-Associated CD10(+) Fibroblasts Have Stronger Interactions with CD133(+) Colon Cancer Cells than with CD133(−) Cancer Cells
por: Cui, Lin, et al.
Publicado: (2010)

Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse
por: Kahlert, C, et al.
Publicado: (2009)

Cell Adhesion Molecule CD166/ALCAM Functions Within the Crypt to Orchestrate Murine Intestinal Stem Cell Homeostasis
por: Smith, Nicholas R., et al.
Publicado: (2017)

Heterogeneity of Cancer-Associated Fibroblasts and the Tumor Immune Microenvironment in Pancreatic Cancer
por: Shinkawa, Tomohiko, et al.
Publicado: (2022)

Expression Levels of Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) in Primary Breast Carcinoma and Distant Breast Cancer Metastases
por: Ihnen, M., et al.
Publicado: (2010)

LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of Pancreatic Cancer
por: Zheng, Biao, et al.
Publicado: (2020)

LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of Pancreatic Cancer: Erratum
por: Zheng, Biao, et al.
Publicado: (2021)

Robotic Surgery in Gastrointestinal Surgery
por: Ohuchida, Kenoki
Publicado: (2020)

High expression of microRNA-155 is associated with the aggressive malignant behavior of gallbladder carcinoma
por: KONO, HIROSHI, et al.
Publicado: (2013)

Cross-sectional area of psoas muscle as a predictive marker of anastomotic failure in male rectal cancer patients: Japanese single institutional retrospective observational study
por: Mizuuchi, Yusuke, et al.
Publicado: (2022)

Combined endoscopic stenting and laparoscopic stent fixation for benign gastric tube stricture after esophagectomy: a case report
por: Shindo, Koji, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_g3ei0jfftq99kbopn48vv6gkv8