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The mechanism of prion strain propagation

Studies of mammalian prion diseases such as bovine spongiform encephalopathy have suggested that different strains consist of prion proteins with different conformations. Two recent studies of yeast prions have now formally demonstrated that multiple stable protein conformations are the basis of str...

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Detalles Bibliográficos
Autor principal: Telling, Glenn C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416460/
https://www.ncbi.nlm.nih.gov/pubmed/15128438
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author Telling, Glenn C
author_facet Telling, Glenn C
author_sort Telling, Glenn C
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description Studies of mammalian prion diseases such as bovine spongiform encephalopathy have suggested that different strains consist of prion proteins with different conformations. Two recent studies of yeast prions have now formally demonstrated that multiple stable protein conformations are the basis of strain variation.
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spelling pubmed-4164602004-05-22 The mechanism of prion strain propagation Telling, Glenn C Genome Biol Minireview Studies of mammalian prion diseases such as bovine spongiform encephalopathy have suggested that different strains consist of prion proteins with different conformations. Two recent studies of yeast prions have now formally demonstrated that multiple stable protein conformations are the basis of strain variation. BioMed Central 2004 2004-04-22 /pmc/articles/PMC416460/ /pubmed/15128438 Text en Copyright © 2004 BioMed Central Ltd
spellingShingle Minireview
Telling, Glenn C
The mechanism of prion strain propagation
title The mechanism of prion strain propagation
title_full The mechanism of prion strain propagation
title_fullStr The mechanism of prion strain propagation
title_full_unstemmed The mechanism of prion strain propagation
title_short The mechanism of prion strain propagation
title_sort mechanism of prion strain propagation
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416460/
https://www.ncbi.nlm.nih.gov/pubmed/15128438
work_keys_str_mv AT tellingglennc themechanismofprionstrainpropagation
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