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The mechanism of prion strain propagation
Studies of mammalian prion diseases such as bovine spongiform encephalopathy have suggested that different strains consist of prion proteins with different conformations. Two recent studies of yeast prions have now formally demonstrated that multiple stable protein conformations are the basis of str...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416460/ https://www.ncbi.nlm.nih.gov/pubmed/15128438 |
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author | Telling, Glenn C |
author_facet | Telling, Glenn C |
author_sort | Telling, Glenn C |
collection | PubMed |
description | Studies of mammalian prion diseases such as bovine spongiform encephalopathy have suggested that different strains consist of prion proteins with different conformations. Two recent studies of yeast prions have now formally demonstrated that multiple stable protein conformations are the basis of strain variation. |
format | Text |
id | pubmed-416460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-4164602004-05-22 The mechanism of prion strain propagation Telling, Glenn C Genome Biol Minireview Studies of mammalian prion diseases such as bovine spongiform encephalopathy have suggested that different strains consist of prion proteins with different conformations. Two recent studies of yeast prions have now formally demonstrated that multiple stable protein conformations are the basis of strain variation. BioMed Central 2004 2004-04-22 /pmc/articles/PMC416460/ /pubmed/15128438 Text en Copyright © 2004 BioMed Central Ltd |
spellingShingle | Minireview Telling, Glenn C The mechanism of prion strain propagation |
title | The mechanism of prion strain propagation |
title_full | The mechanism of prion strain propagation |
title_fullStr | The mechanism of prion strain propagation |
title_full_unstemmed | The mechanism of prion strain propagation |
title_short | The mechanism of prion strain propagation |
title_sort | mechanism of prion strain propagation |
topic | Minireview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416460/ https://www.ncbi.nlm.nih.gov/pubmed/15128438 |
work_keys_str_mv | AT tellingglennc themechanismofprionstrainpropagation AT tellingglennc mechanismofprionstrainpropagation |