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The BiP Cochaperone ERdj4 Is Required for B Cell Development and Function
ERdj4 is a BiP cochaperone regulated by the unfolded protein response to facilitate degradation of unfolded and/or misfolded proteins in the endoplasmic reticulum. As the unfolded protein response plays a critical role in B cell maturation and antibody production, ERdj4 gene trap mice were generated...
Autores principales: | Fritz, Jill M., Weaver, Timothy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164662/ https://www.ncbi.nlm.nih.gov/pubmed/25222125 http://dx.doi.org/10.1371/journal.pone.0107473 |
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