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Rifampicin resistance mutations in the 81 bp RRDR of rpoB gene in Mycobacterium tuberculosis clinical isolates using Xpert(®)MTB/RIF in Kampala, Uganda: a retrospective study

BACKGROUND: Introduction of Xpert(®) MTB/RIF assay has revolutionalised the diagnosis of tuberculosis (TB) by simultaneously detecting the bacteria and resistance to rifampicin (rif), a surrogate marker for multi-drug resistant TB (MDR-TB) as well as one of the principal first-line anti-tuberculosis...

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Detalles Bibliográficos
Autores principales: Mboowa, Gerald, Namaganda, Carolyn, Ssengooba, Willy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164707/
https://www.ncbi.nlm.nih.gov/pubmed/25190040
http://dx.doi.org/10.1186/1471-2334-14-481