Cargando…
c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells
BACKGROUND: Hard consistency, developed under the influence of tumor cell factors, is a characteristic feature of a breast tumor. Activation of resident fibroblasts leading to a myofibroblast phenotype is the principal feature that orchestrates this fibrotic process. The aim of this study was to ass...
Autores principales: | Tobar, Nicolás, Toyos, Marcela, Urra, Carla, Méndez, Nicolás, Arancibia, Rodrigo, Smith, Patricio C, Martínez, Jorge |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164761/ https://www.ncbi.nlm.nih.gov/pubmed/25175743 http://dx.doi.org/10.1186/1471-2407-14-640 |
Ejemplares similares
-
NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration
por: Tobar, N, et al.
Publicado: (2010) -
TNF-Alpha Promotes an Inflammatory Mammary Microenvironment That Favors Macrophage and Epithelial Migration in a CCL2- and Mitochondrial-ROS-Dependent Manner
por: Vera, María Jesús, et al.
Publicado: (2023) -
c-Jun-N-Terminal Kinase Signaling Is Involved in Cyclosporine-Induced Epithelial Phenotypic Changes
por: Pallet, Nicolas, et al.
Publicado: (2012) -
Hyperoside exerts osteoprotective effect on dexamethasone-induced osteoblasts by targeting NADPH Oxidase 4 (NOX4) to inhibit the reactive oxygen species (ROS) accumulation and activate c-Jun N-terminal kinase (JNK) pathway
por: Fan, Siqi, et al.
Publicado: (2022) -
c-Jun N-terminal kinase 2 suppresses pancreatic cancer growth and invasion and is opposed by c-Jun N-terminal kinase 1
por: Tian, Xiaodong, et al.
Publicado: (2021)