Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes

Telomeric RNAs (TERRAs) are UUAGGG repeat-containing RNAs that are transcribed from the subtelomere towards the telomere. The precise genomic origin of TERRA has remained elusive. Using a whole-genome RNA-sequencing approach, we identify novel mouse transcripts arising mainly from the subtelomere of...

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Detalles Bibliográficos
Autores principales: de Silanes, Isabel López, Graña, Osvaldo, De Bonis, Maria Luigia, Dominguez, Orlando, Pisano, David G, Blasco, Maria A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164772/
https://www.ncbi.nlm.nih.gov/pubmed/25182072
http://dx.doi.org/10.1038/ncomms5723

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