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Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex
During cerebral cortex development, pyramidal neurons migrate through the intermediate zone and integrate into the cortical plate. These neurons undergo the multipolar–bipolar transition to initiate radial migration. While perturbation of this polarity acquisition leads to cortical malformations, ho...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164783/ https://www.ncbi.nlm.nih.gov/pubmed/25189171 http://dx.doi.org/10.1038/ncomms5826 |