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In vitro and in vivo antischistosomal activity of ferroquine derivatives

BACKGROUND: Schistosomiasis is a neglected tropical disease and drug-repurposing is a useful strategy to fill its exhausted drug development pipeline. The ferrocenyl analogue of chloroquine, ferroquine, is an antimalarial in late-stage drug development. The aim of the present work was to study the a...

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Detalles Bibliográficos
Autores principales: Keiser, Jennifer, Vargas, Mireille, Rubbiani, Riccardo, Gasser, Gilles, Biot, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164798/
https://www.ncbi.nlm.nih.gov/pubmed/25190030
http://dx.doi.org/10.1186/1756-3305-7-424

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