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Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer
BACKGROUND: Mathematical modelling and analysis is now accepted in the engineering design on par with experimental approaches. Computer simulations enable one to perform several 'what-if' analyses cost effectively. High speed computers and low cost of memory has helped in simulating large-...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416480/ https://www.ncbi.nlm.nih.gov/pubmed/15113442 http://dx.doi.org/10.1186/1471-2407-4-17 |
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author | Ng, Eddie Y-K Sudharsan, NM |
author_facet | Ng, Eddie Y-K Sudharsan, NM |
author_sort | Ng, Eddie Y-K |
collection | PubMed |
description | BACKGROUND: Mathematical modelling and analysis is now accepted in the engineering design on par with experimental approaches. Computer simulations enable one to perform several 'what-if' analyses cost effectively. High speed computers and low cost of memory has helped in simulating large-scale models in a relatively shorter time frame. The possibility of extending numerical modelling in the area of breast cancer detection in conjunction with medical thermography is considered in this work. METHODS: Thermography enables one to see the temperature pattern and look for abnormality. In a thermogram there is no radiation risk as it only captures the infrared radiation from the skin and is totally painless. But, a thermogram is only a test of physiology, whereas a mammogram is a test of anatomy. It is hoped that a thermogram along with numerical modelling will serve as an adjunct tool. Presently mammogram is the 'gold-standard' in breast cancer detection. But the interpretation of a mammogram is largely dependent on the radiologist. Therefore, a thermogram that looks into the physiological changes in combination with numerical simulation performing 'what-if' analysis could act as an adjunct tool to mammography. RESULTS: The proposed framework suggested that it could reduce the occurrence of false-negative/positive cases. CONCLUSION: A numerical bioheat model of a female breast is developed and simulated. The results are compared with experimental results. The possibility of this method as an early detection tool is discussed. |
format | Text |
id | pubmed-416480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-4164802004-05-23 Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer Ng, Eddie Y-K Sudharsan, NM BMC Cancer Research Article BACKGROUND: Mathematical modelling and analysis is now accepted in the engineering design on par with experimental approaches. Computer simulations enable one to perform several 'what-if' analyses cost effectively. High speed computers and low cost of memory has helped in simulating large-scale models in a relatively shorter time frame. The possibility of extending numerical modelling in the area of breast cancer detection in conjunction with medical thermography is considered in this work. METHODS: Thermography enables one to see the temperature pattern and look for abnormality. In a thermogram there is no radiation risk as it only captures the infrared radiation from the skin and is totally painless. But, a thermogram is only a test of physiology, whereas a mammogram is a test of anatomy. It is hoped that a thermogram along with numerical modelling will serve as an adjunct tool. Presently mammogram is the 'gold-standard' in breast cancer detection. But the interpretation of a mammogram is largely dependent on the radiologist. Therefore, a thermogram that looks into the physiological changes in combination with numerical simulation performing 'what-if' analysis could act as an adjunct tool to mammography. RESULTS: The proposed framework suggested that it could reduce the occurrence of false-negative/positive cases. CONCLUSION: A numerical bioheat model of a female breast is developed and simulated. The results are compared with experimental results. The possibility of this method as an early detection tool is discussed. BioMed Central 2004-04-28 /pmc/articles/PMC416480/ /pubmed/15113442 http://dx.doi.org/10.1186/1471-2407-4-17 Text en Copyright © 2004 Ng and Sudharsan; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. |
spellingShingle | Research Article Ng, Eddie Y-K Sudharsan, NM Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer |
title | Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer |
title_full | Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer |
title_fullStr | Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer |
title_full_unstemmed | Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer |
title_short | Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer |
title_sort | computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416480/ https://www.ncbi.nlm.nih.gov/pubmed/15113442 http://dx.doi.org/10.1186/1471-2407-4-17 |
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