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Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer

BACKGROUND: Mathematical modelling and analysis is now accepted in the engineering design on par with experimental approaches. Computer simulations enable one to perform several 'what-if' analyses cost effectively. High speed computers and low cost of memory has helped in simulating large-...

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Autores principales: Ng, Eddie Y-K, Sudharsan, NM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416480/
https://www.ncbi.nlm.nih.gov/pubmed/15113442
http://dx.doi.org/10.1186/1471-2407-4-17
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author Ng, Eddie Y-K
Sudharsan, NM
author_facet Ng, Eddie Y-K
Sudharsan, NM
author_sort Ng, Eddie Y-K
collection PubMed
description BACKGROUND: Mathematical modelling and analysis is now accepted in the engineering design on par with experimental approaches. Computer simulations enable one to perform several 'what-if' analyses cost effectively. High speed computers and low cost of memory has helped in simulating large-scale models in a relatively shorter time frame. The possibility of extending numerical modelling in the area of breast cancer detection in conjunction with medical thermography is considered in this work. METHODS: Thermography enables one to see the temperature pattern and look for abnormality. In a thermogram there is no radiation risk as it only captures the infrared radiation from the skin and is totally painless. But, a thermogram is only a test of physiology, whereas a mammogram is a test of anatomy. It is hoped that a thermogram along with numerical modelling will serve as an adjunct tool. Presently mammogram is the 'gold-standard' in breast cancer detection. But the interpretation of a mammogram is largely dependent on the radiologist. Therefore, a thermogram that looks into the physiological changes in combination with numerical simulation performing 'what-if' analysis could act as an adjunct tool to mammography. RESULTS: The proposed framework suggested that it could reduce the occurrence of false-negative/positive cases. CONCLUSION: A numerical bioheat model of a female breast is developed and simulated. The results are compared with experimental results. The possibility of this method as an early detection tool is discussed.
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spelling pubmed-4164802004-05-23 Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer Ng, Eddie Y-K Sudharsan, NM BMC Cancer Research Article BACKGROUND: Mathematical modelling and analysis is now accepted in the engineering design on par with experimental approaches. Computer simulations enable one to perform several 'what-if' analyses cost effectively. High speed computers and low cost of memory has helped in simulating large-scale models in a relatively shorter time frame. The possibility of extending numerical modelling in the area of breast cancer detection in conjunction with medical thermography is considered in this work. METHODS: Thermography enables one to see the temperature pattern and look for abnormality. In a thermogram there is no radiation risk as it only captures the infrared radiation from the skin and is totally painless. But, a thermogram is only a test of physiology, whereas a mammogram is a test of anatomy. It is hoped that a thermogram along with numerical modelling will serve as an adjunct tool. Presently mammogram is the 'gold-standard' in breast cancer detection. But the interpretation of a mammogram is largely dependent on the radiologist. Therefore, a thermogram that looks into the physiological changes in combination with numerical simulation performing 'what-if' analysis could act as an adjunct tool to mammography. RESULTS: The proposed framework suggested that it could reduce the occurrence of false-negative/positive cases. CONCLUSION: A numerical bioheat model of a female breast is developed and simulated. The results are compared with experimental results. The possibility of this method as an early detection tool is discussed. BioMed Central 2004-04-28 /pmc/articles/PMC416480/ /pubmed/15113442 http://dx.doi.org/10.1186/1471-2407-4-17 Text en Copyright © 2004 Ng and Sudharsan; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
spellingShingle Research Article
Ng, Eddie Y-K
Sudharsan, NM
Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer
title Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer
title_full Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer
title_fullStr Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer
title_full_unstemmed Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer
title_short Computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer
title_sort computer simulation in conjunction with medical thermography as an adjunct tool for early detection of breast cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416480/
https://www.ncbi.nlm.nih.gov/pubmed/15113442
http://dx.doi.org/10.1186/1471-2407-4-17
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