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The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models
Obesity-associated diabetes (“diabesity”) in mouse strains is characterized by severe insulin resistance, hyperglycaemia and progressive failure, and loss of beta cells. This condition is observed in inbred obese mouse strains such as the New Zealand Obese (NZO/HlLt and NZO/HlBomDife) or the TALLYHO...
Autores principales: | Joost, Hans-Georg, Schürmann, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164836/ https://www.ncbi.nlm.nih.gov/pubmed/24752583 http://dx.doi.org/10.1007/s00335-014-9514-2 |
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