Negative Regulation of the Androgen Receptor Gene Through a Primate-Specific Androgen Response Element Present in the 5′ UTR

The androgen receptor (AR) is a widely expressed ligand-activated transcription factor which mediates androgen signalling by binding to androgen response elements (AREs) in normal tissue and prostate cancer (PCa). Within tumours, the amount of AR plays a crucial role in determining cell growth, resi...

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Detalles Bibliográficos
Autores principales: Hay, Colin W., Watt, Kate, Hunter, Irene, Lavery, Derek N., MacKenzie, Alasdair, McEwan, Iain J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164857/
https://www.ncbi.nlm.nih.gov/pubmed/24895212
http://dx.doi.org/10.1007/s12672-014-0185-y

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