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The translation elongation factor eEF1A1 couples transcription to translation during heat shock response
Translation elongation factor eEF1A has a well-defined role in protein synthesis. In this study, we demonstrate a new role for eEF1A: it participates in the entire process of the heat shock response (HSR) in mammalian cells from transcription through translation. Upon stress, isoform 1 of eEF1A rapi...
Autores principales: | Vera, Maria, Pani, Bibhusita, Griffiths, Lowri A, Muchardt, Christian, Abbott, Catherine M, Singer, Robert H, Nudler, Evgeny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164936/ https://www.ncbi.nlm.nih.gov/pubmed/25233275 http://dx.doi.org/10.7554/eLife.03164 |
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