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Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells

Currently there are limited treatment options for corneal blindness caused by dysfunctional corneal endothelial cells. The primary treatment involves transplantation of healthy donor human corneal endothelial cells, but a global shortage of donor corneas necessitates other options. Conventional tiss...

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Detalles Bibliográficos
Autores principales: Zhu, Ying-Ting, Li, Fu, Han, Bo, Tighe, Sean, Zhang, Suzhen, Chen, Szu-Yu, Liu, Xin, Tseng, Scheffer C.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164941/
https://www.ncbi.nlm.nih.gov/pubmed/25202030
http://dx.doi.org/10.1083/jcb.201404032