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Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival
Unless mitigated, external and physiological stresses are detrimental for cells, especially in mitosis, resulting in chromosomal missegregation, aneuploidy, or apoptosis. Heat shock proteins (Hsps) maintain protein homeostasis and promote cell survival. Hsps are transcriptionally regulated by heat s...
Autores principales: | Elsing, Alexandra N., Aspelin, Camilla, Björk, Johanna K., Bergman, Heidi A., Himanen, Samu V., Kallio, Marko J., Roos-Mattjus, Pia, Sistonen, Lea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164949/ https://www.ncbi.nlm.nih.gov/pubmed/25202032 http://dx.doi.org/10.1083/jcb.201402002 |
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