Cargando…

CD8(+) Treg cells suppress CD8(+) T cell-responses by IL-10-dependent mechanism during H5N1 influenza virus infection

Although Treg-cell-mediated suppression during infection or autoimmunity has been described, functions of Treg cells during highly pathogenic avian influenza virus infection remain poorly characterized. Here we found that in Foxp3-GFP transgenic mice, CD8(+) Foxp3(+) Treg cells, but not CD4(+) Foxp3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zou, Qiang, Wu, Bing, Xue, Jia, Fan, Xiaoxu, Feng, Congcong, Geng, Shuang, Wang, Ming, Wang, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Immunity to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165276/ https://www.ncbi.nlm.nih.gov/pubmed/24114149 http://dx.doi.org/10.1002/eji.201343583

Ejemplares similares

Type I IFN signaling facilitates the development of IL‐10‐producing effector CD8(+) T cells during murine influenza virus infection
por: Jiang, Li, et al.
Publicado: (2016)

Avidity of influenza-specific memory CD8(+) T-cell populations decays over time compromising antiviral immunity
por: Humphreys, Ian R, et al.
Publicado: (2012)

IL‐7 induces sCD127 release and mCD127 downregulation in human CD8(+) T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection
por: Côté, Sandra C., et al.
Publicado: (2020)

Monocyte‐derived dendritic cells enhance protection against secondary influenza challenge by controlling the switch in CD8(+) T‐cell immunodominance
por: Cruz, Jazmina L. G., et al.
Publicado: (2016)

Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells
por: Humphreys, Ian R, et al.
Publicado: (2010)

CD8(+) T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity
por: MacHugh, Niall D, et al.
Publicado: (2009)

Upregulation of CCR4 in activated CD8(+) T cells indicates enhanced lung homing in patients with severe acute SARS‐CoV‐2 infection
por: Spoerl, Silvia, et al.
Publicado: (2021)

CD161(++)CD8(+) T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner
por: Ussher, James E, et al.
Publicado: (2014)

Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection
por: Finney, Constance A M, et al.
Publicado: (2007)

IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo
por: Smith, Katherine A, et al.
Publicado: (2014)

Helminth-induced CD19(+)CD23(hi) B cells modulate experimental allergic and autoimmune inflammation
por: Wilson, Mark S, et al.
Publicado: (2010)

CD59a deficiency exacerbates influenza-induced lung inflammation through complement-dependent and-independent mechanisms
por: Longhi, M Paula, et al.
Publicado: (2007)

Batf3-dependent CD103(+) dendritic cells are major producers of IL-12 that drive local Th1 immunity against Leishmania major infection in mice
por: Martínez-López, María, et al.
Publicado: (2015)

CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells
por: Reinink, Peter, et al.
Publicado: (2019)

CD28 and CD57 define four populations with distinct phenotypic properties within human CD8(+) T cells
por: Pangrazzi, Luca, et al.
Publicado: (2019)

Long-Lived CD4(+)IFN-γ(+) T Cells rather than Short-Lived CD4(+)IFN-γ(+)IL-10(+) T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection
por: Villegas-Mendez, Ana, et al.
Publicado: (2016)

Early production of IL‐17A by γδ T cells in the trachea promotes viral clearance during influenza infection in mice
por: Palomino‐Segura, Miguel, et al.
Publicado: (2019)

ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection
por: Redpath, Stephen A, et al.
Publicado: (2013)

Expression of IL‐7Rα and KLRG1 defines functionally distinct CD8(+) T‐cell populations in humans
por: Remmerswaal, Ester B. M., et al.
Publicado: (2019)

Heterologous vaccination against human tuberculosis modulates antigen-specific CD4(+) T-cell function
por: Dintwe, One B, et al.
Publicado: (2013)

Periodontitis‐associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL‐17 responses
por: Cheng, Wan‐Chien, et al.
Publicado: (2016)

HIV-1 infection alters CD4(+) memory T-cell phenotype at the site of disease in extrapulmonary tuberculosis
por: Matthews, Kerryn, et al.
Publicado: (2012)

LCMV‐specific CD4 T cell dependent polyclonal B‐cell activation upon persistent viral infection is short lived and extrafollicular
por: Greczmiel, Ute, et al.
Publicado: (2019)

IKZF3/Aiolos Is Associated with but Not Sufficient for the Expression of IL-10 by CD4(+) T Cells
por: Ridley, Michael L., et al.
Publicado: (2020)

Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4(+) T-cell immunity
por: Pembroke, Tom, et al.
Publicado: (2012)

ICOS is required for the generation of both central and effector CD4(+) memory T‐cell populations following acute bacterial infection
por: Marriott, Clare L., et al.
Publicado: (2015)

Broadly reactive human CD4(+) T cells against Enterobacteriaceae are found in the naïve repertoire and are clonally expanded in the memory repertoire
por: Cassotta, Antonino, et al.
Publicado: (2020)

IL-18, but not IL-15, contributes to the IL-12-dependent induction of NK-cell effector functions by Leishmania infantum in vivo
por: Haeberlein, Simone, et al.
Publicado: (2010)

Combining bempegaldesleukin (CD122-preferential IL-2 pathway agonist) and NKTR-262 (TLR7/8 agonist) improves systemic antitumor CD8(+) T cell cytotoxicity over BEMPEG+RT
por: Rolig, Annah S, et al.
Publicado: (2022)

Essential role of IκB(NS) for in vivo CD4(+) T‐cell activation, proliferation, and Th1‐cell differentiation during Listeria monocytogenes infection in mice
por: Frentzel, Sarah, et al.
Publicado: (2019)

T-bet-mediated differentiation of the activated CD8(+) T cell
por: Yeo, Crystal J J, et al.
Publicado: (2011)

Mycobacterial receptor, Clec4d (CLECSF8, MCL), is coregulated with Mincle and upregulated on mouse myeloid cells following microbial challenge
por: Kerscher, Bernhard, et al.
Publicado: (2015)

CD8(+) chimeric antigen receptor T cells manufactured in absence of CD4(+) cells exhibit hypofunctional phenotype
por: Lee, Sang Yun, et al.
Publicado: (2023)

Surprisingly Effective Priming of CD8(+) T Cells by Heat-Inactivated Vaccinia Virus Virions
por: Croft, Sarah, et al.
Publicado: (2020)

Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells
por: D'Angeli, Vanessa, et al.
Publicado: (2022)

Tumor-specific CD4(+) T cells maintain effector and memory tumor-specific CD8(+) T cells
por: Church, Sarah E, et al.
Publicado: (2014)

CD200R1 regulates eosinophilia during pulmonary fungal infection in mice
por: Salek‐Ardakani, Samira, et al.
Publicado: (2019)

CD45.1/CD45.2 Congenic Markers Induce a Selective Bias for CD8(+) T Cells during Adoptive Lymphocyte Reconstitution in Lymphocytopenia Mice
por: Kalari Kandy, Rakhee Rathnam, et al.
Publicado: (2023)

Nonhuman TRIM5 Variants Enhance Recognition of HIV-1-Infected Cells by CD8(+) T Cells
por: Jimenez-Moyano, Esther, et al.
Publicado: (2016)

IL-21 Promotes CD4 T Cell Responses by Phosphatidylinositol 3-Kinase–Dependent Upregulation of CD86 on B Cells
por: Attridge, Kesley, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hcanosm5ge3s99vmcq0a4reute