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Statistical methods for detecting differentially methylated loci and regions

DNA methylation, the reversible addition of methyl groups at CpG dinucleotides, represents an important regulatory layer associated with gene expression. Changed methylation status has been noted across diverse pathological states, including cancer. The rapid development and uptake of microarrays an...

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Detalles Bibliográficos
Autores principales:	Robinson, Mark D., Kahraman, Abdullah, Law, Charity W., Lindsay, Helen, Nowicka, Malgorzata, Weber, Lukas M., Zhou, Xiaobei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165320/ https://www.ncbi.nlm.nih.gov/pubmed/25278959 http://dx.doi.org/10.3389/fgene.2014.00324

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