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Longitudinal analysis of the behavioral phenotype in a novel transgenic rat model of early stages of Alzheimer's disease

Intraneuronal accumulation of amyloid β (iAβ) has been linked to mild cognitive impairment that may precede Alzheimer's disease (AD) onset. This neuropathological trait was recently mimicked in a novel animal model of AD, the hemizygous transgenic McGill-R-Thy1-APP (Tg(+/−)) rat. The characteri...

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Detalles Bibliográficos
Autores principales:	Galeano, Pablo, Martino Adami, Pamela V., Do Carmo, Sonia, Blanco, Eduardo, Rotondaro, Cecilia, Capani, Francisco, Castaño, Eduardo M., Cuello, A. Claudio, Morelli, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165352/ https://www.ncbi.nlm.nih.gov/pubmed/25278855 http://dx.doi.org/10.3389/fnbeh.2014.00321

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