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A systems biology approach reveals a link between systemic cytokines and skeletal muscle energy metabolism in a rodent smoking model and human COPD
BACKGROUND: A relatively large percentage of patients with chronic obstructive pulmonary disease (COPD) develop systemic co-morbidities that affect prognosis, among which muscle wasting is particularly debilitating. Despite significant research effort, the pathophysiology of this important extrapulm...
Autores principales: | Davidsen, Peter K, Herbert, John M, Antczak, Philipp, Clarke, Kim, Ferrer, Elisabet, Peinado, Victor I, Gonzalez, Constancio, Roca, Josep, Egginton, Stuart, Barberá, Joan A, Falciani, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165371/ https://www.ncbi.nlm.nih.gov/pubmed/25228925 http://dx.doi.org/10.1186/s13073-014-0059-5 |
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