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Nutritional status modulates box C/D snoRNP biogenesis by regulated subcellular relocalization of the R2TP complex

BACKGROUND: Box C/D snoRNPs, which are typically composed of box C/D snoRNA and the four core protein components Nop1, Nop56, Nop58, and Snu13, play an essential role in the modification and processing of pre-ribosomal RNA. The highly conserved R2TP complex, comprising the proteins Rvb1, Rvb2, Tah1,...

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Detalles Bibliográficos
Autores principales: Kakihara, Yoshito, Makhnevych, Taras, Zhao, Liang, Tang, Weiwen, Houry, Walid A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165372/
https://www.ncbi.nlm.nih.gov/pubmed/25060708
http://dx.doi.org/10.1186/s13059-014-0404-4

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