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Nutritional status modulates box C/D snoRNP biogenesis by regulated subcellular relocalization of the R2TP complex
BACKGROUND: Box C/D snoRNPs, which are typically composed of box C/D snoRNA and the four core protein components Nop1, Nop56, Nop58, and Snu13, play an essential role in the modification and processing of pre-ribosomal RNA. The highly conserved R2TP complex, comprising the proteins Rvb1, Rvb2, Tah1,...
Autores principales: | Kakihara, Yoshito, Makhnevych, Taras, Zhao, Liang, Tang, Weiwen, Houry, Walid A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165372/ https://www.ncbi.nlm.nih.gov/pubmed/25060708 http://dx.doi.org/10.1186/s13059-014-0404-4 |
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