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Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada

BACKGROUND: It is estimated that millions of North Americans would qualify for lung cancer screening and that billions of dollars of national health expenditures would be required to support population-based computed tomography lung cancer screening programs. The decision to implement such programs...

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Autores principales: Cressman, Sonya, Lam, Stephen, Tammemagi, Martin C., Evans, William K., Leighl, Natasha B., Regier, Dean A., Bolbocean, Corneliu, Shepherd, Frances A., Tsao, Ming-Sound, Manos, Daria, Liu, Geoffrey, Atkar-Khattra, Sukhinder, Cromwell, Ian, Johnston, Michael R., Mayo, John R., McWilliams, Annette, Couture, Christian, English, John C., Goffin, John, Hwang, David M., Puksa, Serge, Roberts, Heidi, Tremblay, Alain, MacEachern, Paul, Burrowes, Paul, Bhatia, Rick, Finley, Richard J., Goss, Glenwood D., Nicholas, Garth, Seely, Jean M., Sekhon, Harmanjatinder S., Yee, John, Amjadi, Kayvan, Cutz, Jean-Claude, Ionescu, Diana N., Yasufuku, Kazuhiro, Martel, Simon, Soghrati, Kamyar, Sin, Don D., Tan, Wan C., Urbanski, Stefan, Xu, Zhaolin, Peacock, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165479/
https://www.ncbi.nlm.nih.gov/pubmed/25105438
http://dx.doi.org/10.1097/JTO.0000000000000283
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author Cressman, Sonya
Lam, Stephen
Tammemagi, Martin C.
Evans, William K.
Leighl, Natasha B.
Regier, Dean A.
Bolbocean, Corneliu
Shepherd, Frances A.
Tsao, Ming-Sound
Manos, Daria
Liu, Geoffrey
Atkar-Khattra, Sukhinder
Cromwell, Ian
Johnston, Michael R.
Mayo, John R.
McWilliams, Annette
Couture, Christian
English, John C.
Goffin, John
Hwang, David M.
Puksa, Serge
Roberts, Heidi
Tremblay, Alain
MacEachern, Paul
Burrowes, Paul
Bhatia, Rick
Finley, Richard J.
Goss, Glenwood D.
Nicholas, Garth
Seely, Jean M.
Sekhon, Harmanjatinder S.
Yee, John
Amjadi, Kayvan
Cutz, Jean-Claude
Ionescu, Diana N.
Yasufuku, Kazuhiro
Martel, Simon
Soghrati, Kamyar
Sin, Don D.
Tan, Wan C.
Urbanski, Stefan
Xu, Zhaolin
Peacock, Stuart J.
author_facet Cressman, Sonya
Lam, Stephen
Tammemagi, Martin C.
Evans, William K.
Leighl, Natasha B.
Regier, Dean A.
Bolbocean, Corneliu
Shepherd, Frances A.
Tsao, Ming-Sound
Manos, Daria
Liu, Geoffrey
Atkar-Khattra, Sukhinder
Cromwell, Ian
Johnston, Michael R.
Mayo, John R.
McWilliams, Annette
Couture, Christian
English, John C.
Goffin, John
Hwang, David M.
Puksa, Serge
Roberts, Heidi
Tremblay, Alain
MacEachern, Paul
Burrowes, Paul
Bhatia, Rick
Finley, Richard J.
Goss, Glenwood D.
Nicholas, Garth
Seely, Jean M.
Sekhon, Harmanjatinder S.
Yee, John
Amjadi, Kayvan
Cutz, Jean-Claude
Ionescu, Diana N.
Yasufuku, Kazuhiro
Martel, Simon
Soghrati, Kamyar
Sin, Don D.
Tan, Wan C.
Urbanski, Stefan
Xu, Zhaolin
Peacock, Stuart J.
author_sort Cressman, Sonya
collection PubMed
description BACKGROUND: It is estimated that millions of North Americans would qualify for lung cancer screening and that billions of dollars of national health expenditures would be required to support population-based computed tomography lung cancer screening programs. The decision to implement such programs should be informed by data on resource utilization and costs. METHODS: Resource utilization data were collected prospectively from 2059 participants in the Pan-Canadian Early Detection of Lung Cancer Study using low-dose computed tomography (LDCT). Participants who had 2% or greater lung cancer risk over 3 years using a risk prediction tool were recruited from seven major cities across Canada. A cost analysis was conducted from the Canadian public payer’s perspective for resources that were used for the screening and treatment of lung cancer in the initial years of the study. RESULTS: The average per-person cost for screening individuals with LDCT was $453 (95% confidence interval [CI], $400–$505) for the initial 18-months of screening following a baseline scan. The screening costs were highly dependent on the detected lung nodule size, presence of cancer, screening intervention, and the screening center. The mean per-person cost of treating lung cancer with curative surgery was $33,344 (95% CI, $31,553–$34,935) over 2 years. This was lower than the cost of treating advanced-stage lung cancer with chemotherapy, radiotherapy, or supportive care alone, ($47,792; 95% CI, $43,254–$52,200; p = 0.061). CONCLUSION: In the Pan-Canadian study, the average cost to screen individuals with a high risk for developing lung cancer using LDCT and the average initial cost of curative intent treatment were lower than the average per-person cost of treating advanced stage lung cancer which infrequently results in a cure.
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spelling pubmed-41654792014-09-19 Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada Cressman, Sonya Lam, Stephen Tammemagi, Martin C. Evans, William K. Leighl, Natasha B. Regier, Dean A. Bolbocean, Corneliu Shepherd, Frances A. Tsao, Ming-Sound Manos, Daria Liu, Geoffrey Atkar-Khattra, Sukhinder Cromwell, Ian Johnston, Michael R. Mayo, John R. McWilliams, Annette Couture, Christian English, John C. Goffin, John Hwang, David M. Puksa, Serge Roberts, Heidi Tremblay, Alain MacEachern, Paul Burrowes, Paul Bhatia, Rick Finley, Richard J. Goss, Glenwood D. Nicholas, Garth Seely, Jean M. Sekhon, Harmanjatinder S. Yee, John Amjadi, Kayvan Cutz, Jean-Claude Ionescu, Diana N. Yasufuku, Kazuhiro Martel, Simon Soghrati, Kamyar Sin, Don D. Tan, Wan C. Urbanski, Stefan Xu, Zhaolin Peacock, Stuart J. J Thorac Oncol Original Articles BACKGROUND: It is estimated that millions of North Americans would qualify for lung cancer screening and that billions of dollars of national health expenditures would be required to support population-based computed tomography lung cancer screening programs. The decision to implement such programs should be informed by data on resource utilization and costs. METHODS: Resource utilization data were collected prospectively from 2059 participants in the Pan-Canadian Early Detection of Lung Cancer Study using low-dose computed tomography (LDCT). Participants who had 2% or greater lung cancer risk over 3 years using a risk prediction tool were recruited from seven major cities across Canada. A cost analysis was conducted from the Canadian public payer’s perspective for resources that were used for the screening and treatment of lung cancer in the initial years of the study. RESULTS: The average per-person cost for screening individuals with LDCT was $453 (95% confidence interval [CI], $400–$505) for the initial 18-months of screening following a baseline scan. The screening costs were highly dependent on the detected lung nodule size, presence of cancer, screening intervention, and the screening center. The mean per-person cost of treating lung cancer with curative surgery was $33,344 (95% CI, $31,553–$34,935) over 2 years. This was lower than the cost of treating advanced-stage lung cancer with chemotherapy, radiotherapy, or supportive care alone, ($47,792; 95% CI, $43,254–$52,200; p = 0.061). CONCLUSION: In the Pan-Canadian study, the average cost to screen individuals with a high risk for developing lung cancer using LDCT and the average initial cost of curative intent treatment were lower than the average per-person cost of treating advanced stage lung cancer which infrequently results in a cure. Lippincott Williams & Wilkins 2014-10 2014-09-23 /pmc/articles/PMC4165479/ /pubmed/25105438 http://dx.doi.org/10.1097/JTO.0000000000000283 Text en Copyright © 2014 by the International Association for the Study of Lung Cancer This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
spellingShingle Original Articles
Cressman, Sonya
Lam, Stephen
Tammemagi, Martin C.
Evans, William K.
Leighl, Natasha B.
Regier, Dean A.
Bolbocean, Corneliu
Shepherd, Frances A.
Tsao, Ming-Sound
Manos, Daria
Liu, Geoffrey
Atkar-Khattra, Sukhinder
Cromwell, Ian
Johnston, Michael R.
Mayo, John R.
McWilliams, Annette
Couture, Christian
English, John C.
Goffin, John
Hwang, David M.
Puksa, Serge
Roberts, Heidi
Tremblay, Alain
MacEachern, Paul
Burrowes, Paul
Bhatia, Rick
Finley, Richard J.
Goss, Glenwood D.
Nicholas, Garth
Seely, Jean M.
Sekhon, Harmanjatinder S.
Yee, John
Amjadi, Kayvan
Cutz, Jean-Claude
Ionescu, Diana N.
Yasufuku, Kazuhiro
Martel, Simon
Soghrati, Kamyar
Sin, Don D.
Tan, Wan C.
Urbanski, Stefan
Xu, Zhaolin
Peacock, Stuart J.
Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada
title Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada
title_full Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada
title_fullStr Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada
title_full_unstemmed Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada
title_short Resource Utilization and Costs during the Initial Years of Lung Cancer Screening with Computed Tomography in Canada
title_sort resource utilization and costs during the initial years of lung cancer screening with computed tomography in canada
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165479/
https://www.ncbi.nlm.nih.gov/pubmed/25105438
http://dx.doi.org/10.1097/JTO.0000000000000283
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