Genomic Mining of Prokaryotic Repressors for Orthogonal Logic Gates

Genetic circuits perform computational operations based on interactions between freely diffusing molecules within a cell. When transcription factors are combined to build a circuit, unintended interactions can disrupt its function. Here, we apply “part mining” to build a library of 73 TetR-family re...

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Detalles Bibliográficos
Autores principales: Stanton, Brynne C., Nielsen, Alec A.K., Tamsir, Alvin, Clancy, Kevin, Peterson, Todd, Voigt, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165527/
https://www.ncbi.nlm.nih.gov/pubmed/24316737
http://dx.doi.org/10.1038/nchembio.1411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165527/
https://www.ncbi.nlm.nih.gov/pubmed/24316737
http://dx.doi.org/10.1038/nchembio.1411

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