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Genomic Mining of Prokaryotic Repressors for Orthogonal Logic Gates
Genetic circuits perform computational operations based on interactions between freely diffusing molecules within a cell. When transcription factors are combined to build a circuit, unintended interactions can disrupt its function. Here, we apply “part mining” to build a library of 73 TetR-family re...
Autores principales: | Stanton, Brynne C., Nielsen, Alec A.K., Tamsir, Alvin, Clancy, Kevin, Peterson, Todd, Voigt, Christopher A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165527/ https://www.ncbi.nlm.nih.gov/pubmed/24316737 http://dx.doi.org/10.1038/nchembio.1411 |
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