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Synthesis of Acid-Labile PEG and PEG-Doxorubicin-Conjugate Nanoparticles via Brush-First ROMP

[Image: see text] A panel of acid-labile bis-norbornene cross-linkers was synthesized and evaluated for the formation of acid-degradable brush-arm star polymers (BASPs) via the brush-first ring-opening metathesis polymerization (ROMP) method. An acetal-based cross-linker was identified that, when em...

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Detalles Bibliográficos
Autores principales: Gao, Angela X., Liao, Longyan, Johnson, Jeremiah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165536/
https://www.ncbi.nlm.nih.gov/pubmed/25243099
http://dx.doi.org/10.1021/mz5004097