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Synthesis of Acid-Labile PEG and PEG-Doxorubicin-Conjugate Nanoparticles via Brush-First ROMP
[Image: see text] A panel of acid-labile bis-norbornene cross-linkers was synthesized and evaluated for the formation of acid-degradable brush-arm star polymers (BASPs) via the brush-first ring-opening metathesis polymerization (ROMP) method. An acetal-based cross-linker was identified that, when em...
Autores principales: | Gao, Angela X., Liao, Longyan, Johnson, Jeremiah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165536/ https://www.ncbi.nlm.nih.gov/pubmed/25243099 http://dx.doi.org/10.1021/mz5004097 |
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