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Effects of macroporous monofilament mesh on infection in a contaminated field
BACKGROUND: The aim of this study was to evaluate whether the type of the mesh and proper surgical technique can influence the outcome of a tension-free hernia repair in a contaminated filed. MATERIALS AND METHODS: This study was based on the model of bacterial peritonitis in rats induced with a mix...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165876/ https://www.ncbi.nlm.nih.gov/pubmed/25168297 http://dx.doi.org/10.1007/s00423-014-1225-3 |
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author | Bury, Kamil Śmietański, Maciej Justyna, Bigda Gumiela, Piotr Śmietańska, Anna Irmina Owczuk, Radosław Naumiuk, Łukasz Samet, Alfred Paradziej-Łukowicz, J. |
author_facet | Bury, Kamil Śmietański, Maciej Justyna, Bigda Gumiela, Piotr Śmietańska, Anna Irmina Owczuk, Radosław Naumiuk, Łukasz Samet, Alfred Paradziej-Łukowicz, J. |
author_sort | Bury, Kamil |
collection | PubMed |
description | BACKGROUND: The aim of this study was to evaluate whether the type of the mesh and proper surgical technique can influence the outcome of a tension-free hernia repair in a contaminated filed. MATERIALS AND METHODS: This study was based on the model of bacterial peritonitis in rats induced with a mixture composed of Escherichia coli and Bacteroides fragilis. Two animals were used as a control group without induced peritonitis and 10 animals with mesh implanted inside of the peritoneal cavity. For the 20 animals in the studied group, bacterial fluid was applied into the abdominal cavity together with the mesh implantation. In 10 cases, the mesh was fixed flatly upon the surface of the peritoneum; in the other 10, the mesh was rolled and then fixed within the peritoneal cavity. After 5 weeks, the animals were operated on again, and the meshes, the peritoneal fluid and, if present, any granulomas were taken for bacterial cultivation. RESULTS: The results of the bacterial cultivation of the material from the control group (without mesh) and from the rats with flatly fixed mesh were almost completely negative (0/10 and 1/10, respectively). In 9 out of 10 rats that were exposed to the rolled mesh for 5 weeks, the colonisation of meshes with both B. fragilis and E. coli was found (p < 0.0198). CONCLUSIONS: When properly fixed, flat mesh, even in a contaminated field, may allow for a proper mesh healing and does not influence the ability to cure bacterial peritonitis in an animal model. A bad surgical technique, such as inadequately positioned or rolled mesh, may cause persistent peritoneal bacteraemia. |
format | Online Article Text |
id | pubmed-4165876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-41658762014-09-18 Effects of macroporous monofilament mesh on infection in a contaminated field Bury, Kamil Śmietański, Maciej Justyna, Bigda Gumiela, Piotr Śmietańska, Anna Irmina Owczuk, Radosław Naumiuk, Łukasz Samet, Alfred Paradziej-Łukowicz, J. Langenbecks Arch Surg Original Article BACKGROUND: The aim of this study was to evaluate whether the type of the mesh and proper surgical technique can influence the outcome of a tension-free hernia repair in a contaminated filed. MATERIALS AND METHODS: This study was based on the model of bacterial peritonitis in rats induced with a mixture composed of Escherichia coli and Bacteroides fragilis. Two animals were used as a control group without induced peritonitis and 10 animals with mesh implanted inside of the peritoneal cavity. For the 20 animals in the studied group, bacterial fluid was applied into the abdominal cavity together with the mesh implantation. In 10 cases, the mesh was fixed flatly upon the surface of the peritoneum; in the other 10, the mesh was rolled and then fixed within the peritoneal cavity. After 5 weeks, the animals were operated on again, and the meshes, the peritoneal fluid and, if present, any granulomas were taken for bacterial cultivation. RESULTS: The results of the bacterial cultivation of the material from the control group (without mesh) and from the rats with flatly fixed mesh were almost completely negative (0/10 and 1/10, respectively). In 9 out of 10 rats that were exposed to the rolled mesh for 5 weeks, the colonisation of meshes with both B. fragilis and E. coli was found (p < 0.0198). CONCLUSIONS: When properly fixed, flat mesh, even in a contaminated field, may allow for a proper mesh healing and does not influence the ability to cure bacterial peritonitis in an animal model. A bad surgical technique, such as inadequately positioned or rolled mesh, may cause persistent peritoneal bacteraemia. Springer Berlin Heidelberg 2014-08-29 2014 /pmc/articles/PMC4165876/ /pubmed/25168297 http://dx.doi.org/10.1007/s00423-014-1225-3 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Original Article Bury, Kamil Śmietański, Maciej Justyna, Bigda Gumiela, Piotr Śmietańska, Anna Irmina Owczuk, Radosław Naumiuk, Łukasz Samet, Alfred Paradziej-Łukowicz, J. Effects of macroporous monofilament mesh on infection in a contaminated field |
title | Effects of macroporous monofilament mesh on infection in a contaminated field |
title_full | Effects of macroporous monofilament mesh on infection in a contaminated field |
title_fullStr | Effects of macroporous monofilament mesh on infection in a contaminated field |
title_full_unstemmed | Effects of macroporous monofilament mesh on infection in a contaminated field |
title_short | Effects of macroporous monofilament mesh on infection in a contaminated field |
title_sort | effects of macroporous monofilament mesh on infection in a contaminated field |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165876/ https://www.ncbi.nlm.nih.gov/pubmed/25168297 http://dx.doi.org/10.1007/s00423-014-1225-3 |
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