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Fluorescence Detection of KRAS2 mRNA Hybridization in Lung Cancer Cells with PNA-Peptides Containing an Internal Thiazole Orange

[Image: see text] We previously developed reporter-peptide nucleic acid (PNA)-peptides for sequence-specific radioimaging and fluorescence imaging of particular mRNAs in cells and tumors. However, a direct test for PNA-peptide hybridization with RNA in the cytoplasm would be desirable. Thiazole oran...

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Detalles Bibliográficos
Autores principales:	Sonar, Mahesh V., Wampole, Matthew E., Jin, Yuan-Yuan, Chen, Chang-Po, Thakur, Mathew L., Wickstrom, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166030/ https://www.ncbi.nlm.nih.gov/pubmed/25180641 http://dx.doi.org/10.1021/bc500304m

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