In Vitro and in Vivo Metabolite Profiling of Valnemulin Using Ultraperformance Liquid Chromatography–Quadrupole/Time-of-Flight Hybrid Mass Spectrometry

[Image: see text] Valnemulin, a semisynthetic pleuromutilin derivative related to tiamulin, is broadly used to treat bacterial diseases of animals. Despite its widespread use, metabolism in animals has not yet been fully investigated. To better understand valnemulin biotransformation, in this study,...

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Detalles Bibliográficos
Autores principales: Yang, Shupeng, Shi, Weimin, Hu, Dingfei, Zhang, Suxia, Zhang, Huiyan, Wang, Zhanhui, Cheng, Linli, Sun, Feifei, Shen, Jianzhong, Cao, Xingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166035/
https://www.ncbi.nlm.nih.gov/pubmed/25156794
http://dx.doi.org/10.1021/jf5012402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166035/
https://www.ncbi.nlm.nih.gov/pubmed/25156794
http://dx.doi.org/10.1021/jf5012402

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