Behavioral Models of Tinnitus and Hyperacusis in Animals

The phantom perception of tinnitus and reduced sound-level tolerance associated with hyperacusis have a high comorbidity and can be debilitating conditions for which there are no widely accepted treatments. One factor limiting the development of treatments for tinnitus and hyperacusis is the lack of...

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Autores principales: Hayes, Sarah H., Radziwon, Kelly E., Stolzberg, Daniel J., Salvi, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166233/
https://www.ncbi.nlm.nih.gov/pubmed/25278931
http://dx.doi.org/10.3389/fneur.2014.00179
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author Hayes, Sarah H.
Radziwon, Kelly E.
Stolzberg, Daniel J.
Salvi, Richard J.
author_facet Hayes, Sarah H.
Radziwon, Kelly E.
Stolzberg, Daniel J.
Salvi, Richard J.
author_sort Hayes, Sarah H.
collection PubMed
description The phantom perception of tinnitus and reduced sound-level tolerance associated with hyperacusis have a high comorbidity and can be debilitating conditions for which there are no widely accepted treatments. One factor limiting the development of treatments for tinnitus and hyperacusis is the lack of reliable animal behavioral models of these disorders. Therefore, the purpose of this review is to highlight the current animal models of tinnitus and hyperacusis, and to detail the advantages and disadvantages of each paradigm. To date, this is the first review to include models of both tinnitus and hyperacusis.
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spelling pubmed-41662332014-10-02 Behavioral Models of Tinnitus and Hyperacusis in Animals Hayes, Sarah H. Radziwon, Kelly E. Stolzberg, Daniel J. Salvi, Richard J. Front Neurol Neuroscience The phantom perception of tinnitus and reduced sound-level tolerance associated with hyperacusis have a high comorbidity and can be debilitating conditions for which there are no widely accepted treatments. One factor limiting the development of treatments for tinnitus and hyperacusis is the lack of reliable animal behavioral models of these disorders. Therefore, the purpose of this review is to highlight the current animal models of tinnitus and hyperacusis, and to detail the advantages and disadvantages of each paradigm. To date, this is the first review to include models of both tinnitus and hyperacusis. Frontiers Media S.A. 2014-09-17 /pmc/articles/PMC4166233/ /pubmed/25278931 http://dx.doi.org/10.3389/fneur.2014.00179 Text en Copyright © 2014 Hayes, Radziwon, Stolzberg and Salvi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Hayes, Sarah H.
Radziwon, Kelly E.
Stolzberg, Daniel J.
Salvi, Richard J.
Behavioral Models of Tinnitus and Hyperacusis in Animals
title Behavioral Models of Tinnitus and Hyperacusis in Animals
title_full Behavioral Models of Tinnitus and Hyperacusis in Animals
title_fullStr Behavioral Models of Tinnitus and Hyperacusis in Animals
title_full_unstemmed Behavioral Models of Tinnitus and Hyperacusis in Animals
title_short Behavioral Models of Tinnitus and Hyperacusis in Animals
title_sort behavioral models of tinnitus and hyperacusis in animals
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166233/
https://www.ncbi.nlm.nih.gov/pubmed/25278931
http://dx.doi.org/10.3389/fneur.2014.00179
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