Drug Burden Index in older adults: theoretical and practical issues

Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative...

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Autores principales: Kouladjian, Lisa, Gnjidic, Danijela, Chen, Timothy F, Mangoni, Arduino A, Hilmer, Sarah N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166346/
https://www.ncbi.nlm.nih.gov/pubmed/25246778
http://dx.doi.org/10.2147/CIA.S66660
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author Kouladjian, Lisa
Gnjidic, Danijela
Chen, Timothy F
Mangoni, Arduino A
Hilmer, Sarah N
author_facet Kouladjian, Lisa
Gnjidic, Danijela
Chen, Timothy F
Mangoni, Arduino A
Hilmer, Sarah N
author_sort Kouladjian, Lisa
collection PubMed
description Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing.
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spelling pubmed-41663462014-09-22 Drug Burden Index in older adults: theoretical and practical issues Kouladjian, Lisa Gnjidic, Danijela Chen, Timothy F Mangoni, Arduino A Hilmer, Sarah N Clin Interv Aging Review Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing. Dove Medical Press 2014-09-09 /pmc/articles/PMC4166346/ /pubmed/25246778 http://dx.doi.org/10.2147/CIA.S66660 Text en © 2014 Kouladjian et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Kouladjian, Lisa
Gnjidic, Danijela
Chen, Timothy F
Mangoni, Arduino A
Hilmer, Sarah N
Drug Burden Index in older adults: theoretical and practical issues
title Drug Burden Index in older adults: theoretical and practical issues
title_full Drug Burden Index in older adults: theoretical and practical issues
title_fullStr Drug Burden Index in older adults: theoretical and practical issues
title_full_unstemmed Drug Burden Index in older adults: theoretical and practical issues
title_short Drug Burden Index in older adults: theoretical and practical issues
title_sort drug burden index in older adults: theoretical and practical issues
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166346/
https://www.ncbi.nlm.nih.gov/pubmed/25246778
http://dx.doi.org/10.2147/CIA.S66660
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