Cargando…

Seminal plasma induces the expression of IL-1α in normal and neoplastic cervical cells via EP2/EGFR/PI3K/AKT pathway

BACKGROUND: Cervical cancer is a chronic inflammatory disease of multifactorial etiology usually presenting in sexually active women. Exposure of neoplastic cervical epithelial cells to seminal plasma (SP) has been shown to promote the growth of cancer cells in vitro and tumors in vivo by inducing t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adefuye, Anthonio O, Sales, Kurt J, Katz, Arieh A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166412/ https://www.ncbi.nlm.nih.gov/pubmed/25237386 http://dx.doi.org/10.1186/1750-2187-9-8

Ejemplares similares

The Regulation of Inflammatory Pathways and Infectious Disease of the Cervix by Seminal Fluid
por: Adefuye, Anthonio, et al.
Publicado: (2014)

Seminal Fluid-Mediated Inflammation in Physiology and Pathology of the Female Reproductive Tract
por: Adefuye, Anthonio O., et al.
Publicado: (2016)

Seminal Plasma Enhances Cervical Adenocarcinoma Cell Proliferation and Tumour Growth In Vivo
por: Sutherland, Jason R., et al.
Publicado: (2012)

Regulation of Inflammatory Pathways in Cancer and Infectious Disease of the Cervix
por: Adefuye, Anthonio, et al.
Publicado: (2012)

Human errors and factors that influence patient safety in the pre-hospital emergency care setting: Perspectives of South African emergency care practitioners
por: Rowland, Mugsien, et al.
Publicado: (2022)

An Evaluation of Pre-Hospital Emergency Care Personnel Knowledge About Crisis Resource Management and Perspectives of Educators About Inclusion of Crisis Resource Management in the Pre-Hospital Emergency Care Curriculum
por: Rowland, Mugsien, et al.
Publicado: (2022)

Phytochemical analysis and antibacterial evaluation of the ethyl acetate extract of the stem bark of Bridelia micrantha
por: Adefuye, Anthonio O., et al.
Publicado: (2013)

Assessing the knowledge of emergency medical care personnel in the Free State, South Africa, on aspects of paediatric pre-hospital emergency care
por: Butler, Markes Wayne, et al.
Publicado: (2019)

A classic case suggestive of an unruptured ectopic pregnancy with unexpected finding of a unilateral dermoid cyst intraoperatively: A case report
por: Benedict, Matthew A., et al.
Publicado: (2020)

Profile of geriatric presentations at the emergency department of a rural district hospital in South Africa
por: Benedict, Matthew Olukayode Abiodun, et al.
Publicado: (2020)

More than myalgia: An unusual presentation of exertional rhabdomyolysis
por: Benedict, Matthew O.A., et al.
Publicado: (2021)

IL-11 mediates the Radioresistance of Cervical Cancer Cells via the PI3K/Akt Signaling Pathway
por: Sun, Ruige, et al.
Publicado: (2021)

Normal and Neoplastic Hematopoiesis
por: Morin, Michael J.
Publicado: (1984)

The physician-scientists: rare species in Africa
por: Adefuye, Anthonio Oladele, et al.
Publicado: (2018)

The economic burden of deliberate self-poisoning: insight from a tertiary hospital in the Free State Province, South Africa
por: Benedict, Matthew Abiodun, et al.
Publicado: (2020)

Assessing the knowledge of emergency medical care practitioners in the Free State, South Africa, on aspects of pre-hospital management of psychiatric emergencies
por: Mothibi, Jani Daniel, et al.
Publicado: (2019)

The COVID-19 pandemic: the benefits and challenges it presents for medical education in Africa
por: Adefuye, Anthonio Oladele, et al.
Publicado: (2021)

The need to combat stigmatizing dogmas in the midst of the novel coronavirus disease (COVID-19) pandemic
por: Adefuye, Anthonio Oladele, et al.
Publicado: (2020)

Inflammatory Cytokine Profiles of Semen Influence Cytokine Responses of Cervicovaginal Epithelial Cells
por: Rametse, Cosnet L., et al.
Publicado: (2018)

Targeting EGFR/PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma
por: Bang, Jieun, et al.
Publicado: (2023)

The dentist-scientist career pathway in Africa: opportunities and obstacles
por: Adeola, Henry Ademola, et al.
Publicado: (2018)

Students’ Perspectives of a Community-Based Medical Education Programme in a Rural District Hospital
por: Adefuye, Anthonio, et al.
Publicado: (2019)

Factors influencing HIV risk-taking behaviours amongst textile factory workers living with HIV in Lesotho
por: Mabathoana, Refiloe Stephania, et al.
Publicado: (2019)

Neoplastic and Normal Cells in Culture
por: Freshney, R. I.
Publicado: (1981)

Neoplastic and Normal Cells in Culture
por: Frank, David A.
Publicado: (1981)

Polyamines in Normal and Neoplastic Growth
por: O'Connor, P. J.
Publicado: (1976)

Normal and Neoplastic Stem Cells
por: Mccracken, Melissa N., et al.
Publicado: (2017)

The need for nationally accepted guidelines for undergraduate nuclear medicine teaching in MBChB programmes in South Africa
por: Adefuye, Anthonio O., et al.
Publicado: (2020)

Anti-neoplastic action of Cimetidine/Vitamin C on histamine and the PI3K/AKT/mTOR pathway in Ehrlich breast cancer
por: Ibrahim, Sherihan Salaheldin Abdelhamid, et al.
Publicado: (2022)

The effect of erythropoietin on normal and neoplastic cells
por: Elliott, Steve, et al.
Publicado: (2012)

Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance
por: Chang, Kwang-Yu, et al.
Publicado: (2013)

JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation
por: Zhang, Bo, et al.
Publicado: (2021)

SKA3 promotes lung adenocarcinoma metastasis through the EGFR–PI3K–Akt axis
por: Hu, Dan-dan, et al.
Publicado: (2020)

SCD1 is required for EGFR-targeting cancer therapy of lung cancer via re-activation of EGFR/PI3K/AKT signals
por: She, Kelin, et al.
Publicado: (2019)

Current norms and practices in using a seizure diary for managing epilepsy: A scoping review
por: Egenasi, Chika K., et al.
Publicado: (2022)

Seminal plasma hexosaminidase in patients with normal and abnormal spermograms
por: Menendez-Helman, Renata Julia, et al.
Publicado: (2015)

Expression of adipokines in seminal fluid of men of normal weight
por: Bongrani, Alice, et al.
Publicado: (2019)

Tobacco Exposure Enhances Human Papillomavirus 16 Oncogene Expression via EGFR/PI3K/Akt/c-Jun Signaling Pathway in Cervical Cancer Cells
por: Muñoz, Juan P., et al.
Publicado: (2018)

Metapristone (RU486 metabolite) suppresses NSCLC by targeting EGFR-mediated PI3K/AKT pathway
por: Shao, Jingwei, et al.
Publicado: (2017)

CAV2 promotes the growth of renal cell carcinoma through the EGFR/PI3K/Akt pathway
por: Liu, Fu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4nd5iegcqimak7uijvumt4dbi9