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Rapid establishment of a HEK 293 cell line expressing FVIII-BDD using AAV site-specific integration plasmids

BACKGROUND: Stable human cell lines have gradually become the preferred system for large scale production of recombinant proteins for clinical applications because of their capacity of proper protein post-translational modification and low immunogenicity. However, human cell line development technol...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaomei, Ping, Han, Zhang, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166473/ https://www.ncbi.nlm.nih.gov/pubmed/25204455 http://dx.doi.org/10.1186/1756-0500-7-626

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