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Archaerhodopsin Variants with Enhanced Voltage Sensitive Fluorescence in Mammalian and Caenorhabditis elegans Neurons
Probing the neural circuit dynamics underlying behavior would benefit greatly from improved genetically encoded voltage indicators. The proton pump Archaerhodopsin-3 (Arch), an optogenetic tool commonly used for neuronal inhibition, has been shown to emit voltage sensitive fluorescence. Here we repo...
Autores principales: | Flytzanis, Nicholas C., Bedbrook, Claire N., Chiu, Hui, Engqvist, Martin K. M., Xiao, Cheng, Chan, Ken Y., Sternberg, Paul W., Arnold, Frances H., Gradinaru, Viviana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166526/ https://www.ncbi.nlm.nih.gov/pubmed/25222271 http://dx.doi.org/10.1038/ncomms5894 |
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