A distal region of the human TGM1 promoter is required for expression in transgenic mice and cultured keratinocytes

BACKGROUND: TGM1(transglutaminase 1) is an enzyme that crosslinks the cornified envelope of mature keratinocytes. Appropriate expression of the TGM1 gene is crucial for proper keratinocyte function as inactivating mutations lead to the debilitating skin disease, lamellar ichthyosis. TGM1 is also exp...

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Detalles Bibliográficos
Autores principales: Phillips, Marjorie A, Jessen, Bart A, Lu, Ying, Qin, Qin, Stevens, Mary E, Rice, Robert H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416661/
https://www.ncbi.nlm.nih.gov/pubmed/15061870
http://dx.doi.org/10.1186/1471-5945-4-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416661/
https://www.ncbi.nlm.nih.gov/pubmed/15061870
http://dx.doi.org/10.1186/1471-5945-4-2

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