Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica

INTRODUCTION: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs. MATERIALS AND METHODS: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. c...

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Autores principales: Lizundia, Regina, Picado, Albert, Cordero, Marlen, Calderón, Alejandra, Deborggraeve, Stijn, Montenegro, Victor M., Urbina, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166795/
https://www.ncbi.nlm.nih.gov/pubmed/25250232
http://dx.doi.org/10.4103/2229-5070.138539
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author Lizundia, Regina
Picado, Albert
Cordero, Marlen
Calderón, Alejandra
Deborggraeve, Stijn
Montenegro, Victor M.
Urbina, Andrea
author_facet Lizundia, Regina
Picado, Albert
Cordero, Marlen
Calderón, Alejandra
Deborggraeve, Stijn
Montenegro, Victor M.
Urbina, Andrea
author_sort Lizundia, Regina
collection PubMed
description INTRODUCTION: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs. MATERIALS AND METHODS: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica. RESULTS: T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs.
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spelling pubmed-41667952014-09-23 Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica Lizundia, Regina Picado, Albert Cordero, Marlen Calderón, Alejandra Deborggraeve, Stijn Montenegro, Victor M. Urbina, Andrea Trop Parasitol Original Article INTRODUCTION: Chagas disease is a zoonotic disease caused by Trypanosoma cruzi and dogs are one of the main domestic reservoirs. MATERIALS AND METHODS: One molecular (OligoC-TesT, Coris Bioconcept) and one serological (T. cruzi-Detect, Inbios) rapid tests were evaluated as infection markers for T. cruzi in 102 dogs living in eight villages endemic for Chagas in Costa Rica. RESULTS: T. cruzi-Detect performed well as screening tool with 23.3% positive samples. The large number of invalid results (66.7%) observed in samples tested with OligoC-TesT precluded assessing the use of this new method as epidemiological tool to detect T. cruzi infection in dogs. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4166795/ /pubmed/25250232 http://dx.doi.org/10.4103/2229-5070.138539 Text en Copyright: © Tropical Parasitology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lizundia, Regina
Picado, Albert
Cordero, Marlen
Calderón, Alejandra
Deborggraeve, Stijn
Montenegro, Victor M.
Urbina, Andrea
Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica
title Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica
title_full Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica
title_fullStr Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica
title_full_unstemmed Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica
title_short Molecular and serological rapid tests as markers of Trypanosoma cruzi infection in dogs in Costa Rica
title_sort molecular and serological rapid tests as markers of trypanosoma cruzi infection in dogs in costa rica
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166795/
https://www.ncbi.nlm.nih.gov/pubmed/25250232
http://dx.doi.org/10.4103/2229-5070.138539
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