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Pituitary stalk interruption syndrome: Case report of three cases with review of literature

Pickardt syndrome (Pickardt-Fahlbusch syndrome) is a rare congenital syndrome characterized by tertiary hypothyroidism caused by the interruption of the portal veins between hypothalamus and adenohypophysis. Typical features of this syndrome are tertiary hypothyroidism with low thyroid stimulating h...

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Autores principales: Gutch, Manish, Kumar, Sukriti, Razi, Syed Mohd, Saran, Sanjay, Gupta, Keshav Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166852/
https://www.ncbi.nlm.nih.gov/pubmed/25250085
http://dx.doi.org/10.4103/1817-1745.139363
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author Gutch, Manish
Kumar, Sukriti
Razi, Syed Mohd
Saran, Sanjay
Gupta, Keshav Kumar
author_facet Gutch, Manish
Kumar, Sukriti
Razi, Syed Mohd
Saran, Sanjay
Gupta, Keshav Kumar
author_sort Gutch, Manish
collection PubMed
description Pickardt syndrome (Pickardt-Fahlbusch syndrome) is a rare congenital syndrome characterized by tertiary hypothyroidism caused by the interruption of the portal veins between hypothalamus and adenohypophysis. Typical features of this syndrome are tertiary hypothyroidism with low thyroid stimulating hormone, hyperprolactinemia and other pituitary hormone deficiencies. Pituitary stalk interruption syndrome is characterized by a triad of thin or interrupted pituitary stalk, aplasia or hypoplasia of the anterior pituitary and absent or ectopic posterior pituitary (EPP) seen on magnetic resonance imaging (MRI). It is a congenital anomaly of pituitary whose exact prevalence is unknown. In some cases, it is restricted to EPP or pituitary stalk interruption. We are presenting the case history along with MRI finding of three children's who presented with short stature and delayed puberty.
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spelling pubmed-41668522014-09-23 Pituitary stalk interruption syndrome: Case report of three cases with review of literature Gutch, Manish Kumar, Sukriti Razi, Syed Mohd Saran, Sanjay Gupta, Keshav Kumar J Pediatr Neurosci Case Report Pickardt syndrome (Pickardt-Fahlbusch syndrome) is a rare congenital syndrome characterized by tertiary hypothyroidism caused by the interruption of the portal veins between hypothalamus and adenohypophysis. Typical features of this syndrome are tertiary hypothyroidism with low thyroid stimulating hormone, hyperprolactinemia and other pituitary hormone deficiencies. Pituitary stalk interruption syndrome is characterized by a triad of thin or interrupted pituitary stalk, aplasia or hypoplasia of the anterior pituitary and absent or ectopic posterior pituitary (EPP) seen on magnetic resonance imaging (MRI). It is a congenital anomaly of pituitary whose exact prevalence is unknown. In some cases, it is restricted to EPP or pituitary stalk interruption. We are presenting the case history along with MRI finding of three children's who presented with short stature and delayed puberty. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4166852/ /pubmed/25250085 http://dx.doi.org/10.4103/1817-1745.139363 Text en Copyright: © Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gutch, Manish
Kumar, Sukriti
Razi, Syed Mohd
Saran, Sanjay
Gupta, Keshav Kumar
Pituitary stalk interruption syndrome: Case report of three cases with review of literature
title Pituitary stalk interruption syndrome: Case report of three cases with review of literature
title_full Pituitary stalk interruption syndrome: Case report of three cases with review of literature
title_fullStr Pituitary stalk interruption syndrome: Case report of three cases with review of literature
title_full_unstemmed Pituitary stalk interruption syndrome: Case report of three cases with review of literature
title_short Pituitary stalk interruption syndrome: Case report of three cases with review of literature
title_sort pituitary stalk interruption syndrome: case report of three cases with review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166852/
https://www.ncbi.nlm.nih.gov/pubmed/25250085
http://dx.doi.org/10.4103/1817-1745.139363
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