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N-n-butyl haloperidol iodide inhibits H(2)O(2)-induced Na(+)/Ca(2+)-exchanger activation via the Na(+)/H(+) exchanger in rat ventricular myocytes

N-n-butyl haloperidol iodide (F(2)), a novel compound, has shown palliative effects in myocardial ischemia/reperfusion (I/R) injury. In this study, we investigated the effects of F(2) on the extracellular signal-regulated kinase kinase (MEK)/extracellular signal-regulated kinase (ERK)/Na(+)/H(+) exc...

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Detalles Bibliográficos
Autores principales: Huang, Yong-Pan, Gao, Fen-Fei, Wang, Bin, Zheng, Fu-Chun, Zhang, Yan-Mei, Chen, Yi-Cun, Huang, Zhan-Qin, Zheng, Yan-Shan, Zhong, Shu-Ping, Shi, Gang-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166912/
https://www.ncbi.nlm.nih.gov/pubmed/25246767
http://dx.doi.org/10.2147/DDDT.S63163