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Imidazole Aldoximes Effective in Assisting Butyrylcholinesterase Catalysis of Organophosphate Detoxification

[Image: see text] Intoxication by organophosphate (OP) nerve agents and pesticides should be addressed by efficient, quickly deployable countermeasures such as antidotes reactivating acetylcholinesterase or scavenging the parent OP. We present here synthesis and initial in vitro characterization of...

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Detalles Bibliográficos
Autores principales:	Sit, Rakesh K., Fokin, Valery V., Amitai, Gabriel, Sharpless, K. Barry, Taylor, Palmer, Radić, Zoran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167068/ https://www.ncbi.nlm.nih.gov/pubmed/24571195 http://dx.doi.org/10.1021/jm401650z

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