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GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images
Molecular analysis has revealed extensive intra-tumor heterogeneity in human cancer samples, but cannot identify cell-to-cell variations within the tissue microenvironment. In contrast, in situ analysis can identify genetic aberrations in phenotypically defined cell subpopulations while preserving t...
Autores principales: | Trinh, Anne, Rye, Inga H, Almendro, Vanessa, Helland, Åslaug, Russnes, Hege G, Markowetz, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167144/ https://www.ncbi.nlm.nih.gov/pubmed/25168174 http://dx.doi.org/10.1186/s13059-014-0442-y |
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